DETERMINATION OF PROPORTIONS OF DIFFERENT TYPES OF ILD ON CLINICAL AND RADIOLOGICAL BASIS IN PATIENTS PRESENTING TO TERTIARY CARE HOSPITAL

Abstract

Objective: The purpose of the research is the determination of different types of ILD on clinical and radiological basis in patients presenting to territory care hospital.

Study Design: Cross Sectional Observational study

Study Duration: 06 months from Oct 2024-March 2025

Study Place: Department of Medicine, CMH Lahore

Methods: 170 patients according to sample size calculator were inducted with suspected interstitial lung disease (ILD). HRCT and clinical evaluations were used for diagnosis and classification into subtypes such as UIP, NSIP, CTD-ILD, and HP. Data on demographics, exposures, and serology were collected. Statistical analysis using SPSS (p < 0.05) determined subtype proportions and associations.

Results: Out of 170 ILD patients, 54.1% were female and 45.9% male, with a mean age of 56.8 ± 12.4 years. Dyspnea (93.5%) and dry cough (86.5%) were the most frequent symptoms. UIP was the most common subtype (38.2%), followed by NSIP (22.4%), HP (12.9%), and sarcoidosis (10%). Clinical and HRCT findings agreed in 78.8% of cases. Most showed restrictive spirometry, with UIP patients having the greatest functional decline

Conclusion: Usual interstitial pneumonia (UIP) is the most common subtype of interstitial lung disease (ILD), followed by nonspecific interstitial pneumonia (NSIP), connective tissue disease–associated ILD (CTD-ILD), and hypersensitivity pneumonitis (HP).