FREQUENCY OF ACUTE KIDNEY INJURY (AKI) IN PATIENTS PRESENTING WITH NEUTROPENIC COLITIS

Abstract

Objective: “To determine the frequency of acute kidney injury in patients admitted with neutropenic colitis”

Study Design: Prospective observational study

Setting and Duration: Department of Internal medicine at Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore from 01 April 2024 to 30 September 2024.

Methodology:

After meeting selection criteria total 73 patients were enrolled and serum creatinine was measured at the time of admission and subsequently at 24-hour intervals for 7 days or until discharge. Urine output was monitored regularly according to hospital guidelines. All patients received management as per the hospital’s neutropenic colitis treatment protocol. Acute kidney injury (AKI) was recorded according to the operational definition. Data analysis was performed using SPSS version 21.

Results:

In this research, the mean age of the cases was 50.76 ± 7.05 years, 39 (53.4%) were males and 34 (46.6%) were females. The mean BMI of patients was 21.65 ± 2.66 kg/m². In this study, AKI was observed in 5 (6.85%) patients admitted with neutropenic colitis.

Conclusion: This research concludes that frequency of AKI among patients admitted with neutropenic colitis was 6.85%