OUTCOME OF ISCHEMIC STROKE IN GOOD CONTROLLED AND POORLY CONTROLLED DIABETIC PATIENTS PRESENTING IN EMERGENCY DEPARTMENT

Abstract

Objective: To determine the frequency of poorly control diabetes in patients with ischemic stroke and then compare the outcome of ischemic stroke in good versus poorly controlled diabetic patients presenting in emergency department

Study design:1Longitudinal study

Study1place1and1period: Department of Medicine, Sahiwal Teaching Hospital, Sahiwal from 01 February 2025 till 30 April 2025.

Methodology: One hundred patients with ischemic stroke were recruited and admitted in medical wards. NIHSS and mRS score were noted at admission and at discharge and later on after 3 months. HbA1c was also assessed to check glycemic control. All this information was recoded on proforma and analyzed in SPSS v.25.

Results: The mean age of patients was 47.27 ± 11.82 years. There were 78 (78%) men and 22 (22%) women. The mean duration of stroke was 13.26 ± 6.71. Out of 100 patients, 78 (78%) patients had poorly controlled glycemic level. Among patients with poorly controlled diabetes, the mean HbA1c level was 10.71 ± 1.77 % vs. 6.68 ± 0.23 % (p<0.05) and fasting glucose level was 112.86 ± 7.42 vs. 106.45 ± 4.54 mg/dl, (p<0.05) that was significantly higher than patients with good controlled diabetes. The mean NIHSS score was 24.36 ± 5.47 vs. 26.50 ± 6.28, at discharge was 19.03 ± 4.49 vs. 15.68 ± 4.72 (p<0.05) and after 3 months was 13.92 ± 4.02 vs. 5.36 ± 3.02 (p<0.05). The mean mRS score was 3.99 ± 0.76 vs. 4.23 ± 0.87 (p>0.05), at discharge was 2.62 ± 0.63 vs. 1.91 ± 0.92 (p<0.05) and after 3 months was 2.00 ± 0.87 vs. 0.32 ± 0.48 (p<0.05), respectively.

Conclusion: The results showed that the poorly controlled diabetes is associated with more severe consequences and more poor outcomes of stroke leading to disability.