30 DAY MORTALITY AMONG PATIENTS WITH ACUTE STROKE (ISCHEMIC AND HEMORRHAGIC) IN A TERTIARY CARE HOSPITAL

Abstract

Objective: To compare 30-day mortality and prognostic factors in acute haemorrhagic and ischemic stroke patients

Study Design: Prospective observational cohort study

Place and Duration of Study: General Medicine and Neurology Department, Pak Emirates Military Hospital, Rawalpindi, January 2024-December 2024

Methodology: Patients from both genders aged 18 years or more with ischemic stroke or haemorrhagic stroke were included. Data were collected from patients within 24 hours of admission and weekly for 30 days after discharge. Any reported mortality was recorded. The initial data collection included age, gender, comorbid conditions, smoking history, alcohol intake, random blood glucose, and other relevant laboratory investigations as ordered by the treating physician. Logistic regression analysis was used to assess the predictors of mortality.

Results: Among the 200 patients, 151 (75.50%) had ischemic stroke, and 49 (24.50%) had haemorrhagic stroke. The mean age in ischemic stroke (IS) was 52.03±13.53 years, while it was somewhat higher, 57.20±12.50 years, in haemorrhagic stroke (HS). Hypertensive patients were more in IS group (59.60% vs 46.94%). Age, gender, hypertension, smoking status, dyslipidaemia, hyperglycaemia, marital status, and stroke subtype were not significantly associated with mortality on univariate analysis. After adjustment for confounders, diabetes mellitus (AOR 0.391, 95% CI 0.160–0.954, p=0.039), alcohol intake (AOR 0.093, 95% CI 0.015–0.589, p=0.012), and ECG abnormalities (AOR 0.350, 95% CI 0.144–0.854, p=0.021) remained independent and strong predictors of mortality

Conclusion: The frequency of mortality was 26 (13.0%) in stroke patients. Diabetes mellitus, alcohol intake, and electrocardiographic abnormalities remained independent predictors of mortality