HYPERPIGMENTATION AFTER MICRONEEDLING VS. CHEMICAL PEEL: A COMPARATIVE STUDY WITH STANDARDIZED AFTERCARE

Main Article Content

Uzma Naeem
Faiqa Zahra
Qandeel Rida

Abstract

Background


Hypertrophic hyperpigmentation, especially melasma, and post-inflammatory hyperpigmentation (PIH) represent a widespread skin problem with a huge number of patients. Hyperpigmentation is usually treated with microneedling and chemical peels. Their synergistic effect on pigmentation has, however, not been fully studied.


Methodology


The research deals with 52 patients (Cross sectional study design) with Group A (treated by Sunblock, Moisturizer, Vitamin C, and azelic acid serum 7 percent) and Group B (treated by Sunblock, Moisturizer, Vitamin C, and Niacinamide Serum). The participants were evaluated on the reduction of hyperpigmentation, the appearance of skin and satisfaction overall.


Objective


To compare the efficacy of combined microneedling and topical therapy in decreasing hyperpigmentation. To compare patient satisfaction and improvement in appearance of two different treatment protocols.


Results:


Group A showed much improved pigmentation reduction (p < 0.05) and improvement in appearance than Group B. Group A patients had a higher level of satisfaction (85%) and adherence to the treatment regimen (90%), along with a better level of improvements in skin texture. The general performance of Group A was better in all the aspects of treatment.


Conclusion:


This study indicates that Azelaic Acid Serum combined with microneedling is a better option to treat hyperpigmentation than Niacinamide Serum. Group A had improved treatment results regarding pigmentation and skin texture and appearance. Future research ought to incorporate bigger sample sizes and extended follow up. Combination therapy can provide a better approach to control hyperpigmentation.

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HYPERPIGMENTATION AFTER MICRONEEDLING VS. CHEMICAL PEEL: A COMPARATIVE STUDY WITH STANDARDIZED AFTERCARE. (2026). The Research of Medical Science Review, 4(5), 223-245. https://medicalsciencereview.com/index.php/Journal/article/view/3601