EFFICACY OF MICRONEEDLING ALONE VERSUS MICRONEEDLING IN COMBINATION WITH SUBCISION AND BIOFILLER INSERTION IN ATROPHIC ACNE SCARE: A SPLIT FACE STUDY

Abstract

Background: Atrophic acne scars are a common cosmetic concern that significantly impact individuals' quality of life. Various treatments, including microneedling, subcision, and biofiller insertion, have been developed to improve scar appearance. However, the comparative efficacy of microneedling alone versus its combination with subcision and biofiller remains underexplored. This split-face study aimed to evaluate the efficacy of microneedling alone compared to microneedling combined with subcision and biofiller insertion in the treatment of atrophic acne scars.

Methods: A total of 70 participants aged 18–40 years with bilateral atrophic acne scars (Goodman and Baron score ≥3) were enrolled in the study and divided in two groups. Each participant of both groups received microneedling on right side of the face (control) and a combination of microneedling, subcision, and PRP (combination) on the left side. Treatments were performed at 1 month interval for 4 sessions followed by two follow ups , each 3 months apart from last session. Outcomes were assessed using the GBS, patient satisfaction survey and observation of side effects.

Results: The combination side (left side of face) showed a significantly greater reduction in GBS compared to the control side (left side of face). Patient satisfaction was higher for the combination therapy, with 70% of participants reporting substantial improvement Both treatments were well-tolerated, with only mild post-inflammatory hyperpigmentation and bruising reported.

Conclusion: The combination of microneedling, subcision, and PRP demonstrated superior efficacy and patient satisfaction compared to microneedling alone in treating atrophic acne scars. This multimodal approach provides a safe and effective option for scar management.