EFFICACY OF INTRAVENOUS XYLOCAINE IN REDUCTION OF PROPOFOL-INDUCED PAIN

Abstract

Objectives: To determine if IV Xylocaine helps in reducing propofol-induced pain in patients undergoing short surgical procedures while under GA (general anesthesia).

Study Design: Descriptive cross-sectional study

Study Setting And Duration: Department of Anesthesia, Ittefaq Hospital Trust Lahore from 01 October 2024 till 31 March 2025.

Methodology: 150 patients aged 18-60 years were scheduled for a short surgical procedure while under GA using non-probability consecutive sampling. Pain severity was assessed using the Visual Analogue Scale (VAS), with a VAS score of < 3 being considered effective. The analysis of data was accomplished using SPSS 26. Quantitative variables were reported as median (IQR), and qualitative variables were reported as frequency and percentage. Additionally, stratification was done in order to evaluate efficacy.

Results:  The average age of the participants was 42 years (range: 26-53), and their average BMI was 25.7 kg/m2 (range: 20.2-31.0). The majority of the patients were male (58.7%), and 52.7% were classified as ASA II. Tonsillectomy was the most frequently performed surgical procedure (36.7%) among the participants. The majority of the patients exhibited lower VAS scores than their pre-procedure scores, with the most frequently reported score of 2 being noted by 24.7% of participants. Overall, a total of 76% of participants had a positive response to the intravenous Xylocaine treatment.

Conclusion:  The results of this study indicate that intravenous Xylocaine is an effective way to reduce the pain associated with propofol during the administration of general anesthesia for short surgical procedures