AN EXAMINATION OF FACTORS AFFECTING DELAYED UNION AND NONUNION IN ORTHOPEDIC TRAUMA PATIENTS

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Imran Khan

Abstract

Delayed union and nonunion remain significant complications in orthopedic trauma patients, leading to prolonged disability, increased healthcare costs, and reduced quality of life. This study examines the factors associated with delayed bone healing and nonunion in patients with traumatic fractures. The primary problem addressed is the increasing incidence of impaired fracture healing despite advances in surgical techniques and fixation methods. The objective of the study is to identify clinical, biological, and mechanical factors that contribute to delay union and nonunion in orthopedic trauma patients. A retrospective observational design was employed, analyzing patient records from orthopedic trauma cases treated in tertiary care hospitals. Data included demographic variables, fracture characteristics, treatment modalities, comorbidities, infection status, smoking history, and fixation techniques. Statistical analysis was performed to determine significant associations between risk factors and healing outcomes. The major results indicate that open fractures, infection, smoking, diabetes mellitus, inadequate stabilization, and poor nutritional status are strongly associated with delayed union and nonunion. Mechanical instability and high-energy trauma were also significant contributors. Among these, infection and smoking showed the highest correlation with impaired healing. In conclusion, both patient-related and treatment-related factors play a critical role in fracture healing outcomes. Early identification of high-risk patients and optimization of modifiable risk factors can significantly improve recovery. The findings highlight the need for multidisciplinary management strategies to reduce the burden of delayed union and nonunion in orthopedic trauma care.

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AN EXAMINATION OF FACTORS AFFECTING DELAYED UNION AND NONUNION IN ORTHOPEDIC TRAUMA PATIENTS. (2026). The Research of Medical Science Review, 4(5), 1049-1060. https://medicalsciencereview.com/index.php/Journal/article/view/3771